Can VVDI2 do Porsche Cayenne 2010+ keyless-go?

Yes, it can be done by eeprom.

Remove BCM and find diagram depending on MCU mask and read in-circuit after removal of appropriate components (if required)

Here’s a great and detailed tutorial with Vvdi prog and vvdi2

Confirmed! VVDI-Prog and VVDI2on Porsche Boxster GTS 2016